Table 1.
Protein name | B-cell epitope sequence | MHC-I epitope sequence | MHC-I binding alleles | VaxiJen score |
---|---|---|---|---|
A | ||||
HpaA | NPSVETKTQNDAKNQQPVQTHERMKTSSEHVTPLDFNYPIHIVQAPQN | HVTPLDFNYP |
HLA-A*0201 HLA-A*0205 HLA-B*2702 HLA-B*3501 HLA-B*3701 HLA-B*3801 HLA-B*0702 |
1.1099 |
GYQVLRFQDEKALSAQDKR | QDEKALSAQ |
HLA-A*1101 HLA-A*3101 HLA-B*2702 HLA-B*5801 |
1.1087 | |
PESNRVVHDFAVEVG | VVHDFAVEV |
HLA-A*0201 HLA-A*0205 HLA-B*3701 HLA-B*4403 HLA-B*5301 |
1.3684 | |
YTYKHSNSGGLDSSNNIIHEALEKNKEDA | KHSNSGGLD |
HLA-B*3902 HLA-B*5301 HLA-B*5401 |
2.2506 | |
FlaA | NALKTSLERLSSGLRINKAAD | RLSSGLRIN |
HLA-B*2702 HLA-B*2705 HLA-B*3901 HLA-B*5801 |
1.5169 |
AAQDGQTTESRKAIQSD | QDGQTTESR |
HLA-B*2702 HLA-B*5101 HLA-B*5801 |
2.9528 | |
VTGNFNANVKSASGANYNAVIASGNQSLGSGVTTLRG | NANVKSASG | HLA-B*5401 | 2.2390 | |
VNNISITQVNVKAAESQIRDV | VNVKAAESQ | HLA-B*5801 | 1.9766 | |
FlaB | QNNRDLSSSLEKLSSGLRINKAADD | KLSSGLRIN |
HLA-A*0205 HLA-B*3901 HLA-B*5801 |
1.5519 |
AQDGQTLESRRALQSDIQRLLEE | QDGQTLESR |
HLA-A*3302 HLA-B*2702 HLA-B*3501 HLA-B*3902 HLA-B*5801 |
2.2153 | |
VRGIFDANVASAAGANANGAQAETNSQGIGAGVTSLKGAM | NANGAQAET |
HLA-B*5101 HLA-B*5103 |
2.4424 | |
ISVTQVNVKAAESQIRDVDF | VNVKAAESQ | HLA-B*5801 | 1.9766 | |
Omp18 | HKMDNKTVAGDVSAKTVQTAPVTTEPAPEKEEPKQEPAPVVEEKPAVESGT | GDVSAKTVQ |
HLA-A*3302 HLA-B*5101 HLA-B*5102 HLA-B*5103 HLA-B*5201 HLA-B*5801 |
1.9177 |
HKMDNKTVAGDVSAKTVQTAPVTTEPAPEKEEPKQEPAPVVEEKPAVESGT | EKEEPKQEP |
HLA-B*4403 HLA-B*0702 |
1.3706 | |
FDFDKYEIKESDQET | EIKESDQET |
HLA-A*3302 HLA-B*3701 HLA-B*3901 HLA-B*3902 HLA-B*4403 HLA-B*5301 |
1.8008 | |
ISFGETKPKCTQKTRECYKEN | GETKPKCTQ |
HLA-A*1101 HLA-A*3101 HLA-B*5401 HLA-B*5801 |
1.7641 |
Sl. No | B-cell epitope sequence | MHC-II epitope sequence | MHC-II binding alleles | VaxiJen score |
---|---|---|---|---|
B | ||||
HpaA | NPSVETKTQNDAKNQQPVQTHERMKTSSEHVTPLDFNYPIHIVQAPQN | VQTHERMKTSSEHVT |
HLA-DRB1*1302 HLA-DRB1*0901 HLA-DRB1*0701 HLA-DRB1*0301 HLA-DRB1*0405 |
1.2231 |
NPSVETKTQNDAKNQQPVQTHERMKTSSEHVTPLDFNYPIHIVQAPQN | PSVETKTQNDAKNQQ |
HLA-DRB1*0802 HLA-DRB1*1302 HLA-DRB4*0101 HLA-DRB3*0101 |
1.6689 | |
GYQVLRFQDEKALSAQDKR | LRFQDEKALSAQDKR |
HLA-DRB1*0401 HLA-DQA1*0401 HLA-DPA1*0103 HLA-DRB5*0101 |
1.1177 | |
YTYKHSNSGGLDSSNNIIHEALEKNKEDA | YTYKHSNSGGLDSSN |
HLA-DRB1*0101 HLA-DQA1*0501 HLA-DRB1*0401 HLA-DRB3*0101 HLA-DRB1*0405 |
1.3437 | |
FlaA | AAQDGQTTESRKAIQSD | QDGQTTESRKAIQSD |
HLA-DQA1*0301 HLA-DQA1*0102 HLA-DQA1*0401 HLA-DRB1*0701 HLA-DQA1*0501 |
1.7622 |
VTGNFNANVKSASGANYNAVIASGNQSLGSGVTTLRG | ASGNQSLGSGVTTLR |
HLA-DQA1*0301 HLA-DPA1*0301 HLA-DRB1*0405 HLA-DQA1*0501 HLA-DPA1*0201 |
1.3656 | |
VTGNFNANVKSASGANYNAVIASGNQSLGSGVTTLRG | NANVKSASGANYNAV |
HLA-DRB1*1101 HLA-DRB3*0101 HLA-DQA1*0301 HLA-DQA1*0501 HLA-DPA1*0103 |
1.6352 | |
VNNISITQVNVKAAESQIRDV | NISITQVNVKAAESQ |
HLA-DQA1*0101 HLA-DRB3*0101 |
1.6160 | |
FlaB | AQDGQTLESRRALQSDIQRLLEE | QDGQTLESRRALQSD |
HLA-DRB1*1101 HLA-DQA1*0102 HLA-DRB1*0802 HLA-DRB1*0301 HLA-DRB1*0901 |
1.2748 |
VRGIFDANVASAAGANANGAQAETNSQGIGAGVTSLKGAM | ETNSQGIGAGVTSLK |
HLA-DQA1*0102 HLA-DQA1*0301 HLA-DRB1*0101 HLA-DQA1*0401 HLA-DRB1*0301 |
1.7236 | |
VRGIFDANVASAAGANANGAQAETNSQGIGAGVTSLKGAM | GANANGAQAETNSQG |
HLA-DRB1*0401 HLA-DQA1*0501 HLA-DRB1*0405 HLA-DRB4*0101 HLA-DPA1*0103 |
2.3765 | |
ISVTQVNVKAAESQIRDVDF | QVNVKAAESQIRDVD |
HLA-DPA1*0103 HLA-DQA1*0101 HLA-DRB1*1201 HLA-DRB1*1501 HLA-DPA1*0301 |
1.6015 | |
Omp18 | HKMDNKTVAGDVSAKTVQTAPVTTEPAPEKEEPKQEPAPVVEEKPAVESGT | KMDNKTVAGDVSAKT |
HLA-DQA1*0501 HLA-DRB1*0401 HLA-DRB1*0802 HLA-DRB3*0101 HLA-DRB1*0301 |
1.7244 |
HKMDNKTVAGDVSAKTVQTAPVTTEPAPEKEEPKQEPAPVVEEKPAVESGT | NKTVAGDVSAKTVQT |
HLA-DQA1*0401 HLA-DRB1*0802 HLA-DQA1*0301 HLA-DRB1*0901 HLA-DRB1*1302 |
1.4458 | |
FDFDKYEIKESDQET | FDFDKYEIKESDQET |
HLA-DPA1*0201 HLA-DPA1*0103 HLA-DRB1*0401 HLA-DRB1*0301 HLA-DRB4*0101 |
1.3271 | |
ISFGETKPKCTQKTRECYKEN | GETKPKCTQKTRECY |
HLA-DRB1*0301 HLA-DRB1*1201 HLA-DRB1*1101 HLA-DRB1*0701 HLA-DRB5*0101 |
1.3419 |