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Influence of Qingfei Paidu decoction on the pharmacokinetics of lopinavir in rats. Mean ± SD of triplicate rats.
| Group | AUC(0-inf) (ng/mL·h) | Cmax (ng/mL) | t1/2 (h) | Tmax (h) |
|---|---|---|---|---|
| Water + lopinavir | 6092 | 1140 | 1.90 | 6.00 |
| QPD + lopinavir | 12429 | 1190 | 2.66 | 8.00 |
| Ratio | 2.04 | 1.04 | 1.40 | 1.33 |
| Increasing (%) | 104 | 4 | 40 | 33 |
