Table 3.
Baseline biomarkers by sex
| Blood tests | Sex |
||||
|---|---|---|---|---|---|
| N | Female | Male | p valuea | Total | |
| Markers, Median (IQR) | |||||
| Haemoglobin, g/dL | 380 | 12.0 (10.5, 13.1) | 13.3 (12.1, 14.2) | <0.001 | 12.8 (11.4, 14.0) |
| White cells, mm3 | 380 | 5760 (4540, 8400) | 6340 (4930, 8520) | 0.27 | 6110 (4810, 8480) |
| Total lymphocytes, N | 264 | 1368 (730.0, 2420) | 1584 (870.0, 2390) | 0.43 | 1545 (857.5, 2405) |
| Total lymphocytes, % | 289 | 20.2 (7.2, 37.5) | 25.4 (11.0, 34.7) | 0.53 | 22.9 (9.1, 35.3) |
| Alanine amino-transferase, U/L | 225 | 31.0 (21.0, 44.0) | 39.0 (27.0, 58.0) | 0.002 | 35.0 (25.0, 54.0) |
| Bilirubin, mg/dL | 370 | 0.4 (0.3, 0.6) | 0.6 (0.5, 0.8) | <0.001 | 0.6 (0.4, 0.8) |
| Calcium, mg/dL | 356 | 8.7 (8.3, 9.1) | 8.6 (8.2, 8.9) | 0.02 | 8.6 (8.2, 9.0) |
| Creatine Kinase, U/L | 375 | 51.5 (33.0, 108.0) | 132.0 (57.0, 282.0) | <0.001 | 88.0 (44.0, 221.0) |
| Chloride, mmol/L | 353 | 100.0 (98.0, 102.0) | 100.0 (98.0, 103.0) | 0.58 | 100.0 (98.0, 103.0) |
| Creatinine, mg/dL | 380 | 0.7 (0.6, 0.9) | 0.9 (0.8, 1.2) | <0.001 | 0.9 (0.7, 1.1) |
| D-dimer, ng/mL | 375 | 1015 (640.0, 2070) | 1160 (640.0, 2210) | 0.59 | 1150 (640.0, 2170) |
| Lactate dehydrogenase, U/L | 379 | 527.0 (397.0, 651.0) | 597.0 (461.5, 767.0) | 0.001 | 563.0 (446.0, 726.0) |
| C-reactive protein, mg/dL | 380 | 5.8 (2.0, 14.4) | 7.5 (4.1, 17.5) | <0.001 | 7.0 (3.2, 16.4) |
| Platelets, 109/L | 380 | 229.0 (166.0, 292.0) | 199.0 (149.0, 269.0) | 0.04 | 207.5 (155.0, 274.5) |
| Potassium, mmol/l | 369 | 3.8 (3.5, 4.2) | 3.8 (3.5, 4.1) | 0.68 | 3.8 (3.5, 4.1) |
| Sodium, mmol/L | 369 | 137.0 (135.0, 139.0) | 137.0 (134.0, 139.0) | 0.56 | 137.0 (135.0, 139.0) |
| IL-6, pg/mL | 262 | 189.7 (67.4, 366.0) | 193.4 (77.2, 399.9) | 0.46 | 191.8 (71.0, 399.9) |
| Ferritin, ng/ml | 244 | 433.5 (207.0, 720.0) | 906.5 (535.0, 1492) | <0.001 | 650.0 (368.0, 1251) |
a
Mann-Whitney test.