Table 4.
Risk Factor | Age Adjusted |
Age- & Troponin-Adjusted Modelb |
Multivariable Modelc Area Under the Curve = 0.81 (0.74-0.88) |
|||
---|---|---|---|---|---|---|
Odds Ratio (95% CI) | P | Odds Ratio (95% CI) | P | Odds Ratio (95% CI) | P | |
Age, per 5 y | 1.06 (0.97-1.16) | .20 | 0.99 (0.90-1.10) | .91 | 0.92 (0.81-1.03) | .16 |
Nonwhite/non-Hispanic | 1.49 (0.79-2.81) | .22 | 1.29 (0.66-2.52) | .46 | ||
Cancer | 3.74 (0.93-15.06) | .06 | 4.65 (1.10-19.48) | .04 | ||
Cardiovascular disease | 2.18 (0.95-4.99) | .07 | 1.85 (0.77-4.44) | .17 | 3.12 (1.20-8.17) | .02 |
Atrial fibrillation/flutter [n=178] | 1.60 (0.53-4.86) | .40 | 1.53 (0.46-5.09) | .49 | ||
Creatinine, per 1 SD [n=159] | 1.77 (1.14-2.75) | .01 | 1.40 (0.89-2.19) | .14 | ||
Troponin, per 1 SD [n=133] | 2.28 (1.36-3.80) | .002 | — | 1.86 (1.16-2.98) | .01 | |
N-terminal prohormone B-type natriuretic peptide, per 1 SD [n=113] | 2.85 (1.71-4.76) | <.001 | 2.53 (1.46-4.39) | .001 | ||
D-Dimer, per 1 SD | 2.41 (1.60-3.65) | <.001 | 2.30 (1.52-3.49) | <.001 | 2.45 (1.59-3.76) | <.001 |
Systolic blood pressure, per 5 mm Hg [n=178] | 0.94 (0.87-1.01) | .10 | 0.95 (0.88-1.03) | .20 | ||
Diastolic blood pressure, per 5 mm Hg [n=177] | 0.85 (0.75-0.97) | .007 | 0.85 (0.75-0.97) | .01 | ||
Ejection fraction, per 5% | 0.92 (0.80-1.05) | .23 | 0.99 (0.85,1.15) | .88 | ||
RWMSI >1 [n=154] | 2.95 (1.21-7.17) | .02 | 1.66 (0.61-4.52) | .32 | ||
RV enlargement [n=175] | 1.51 (0.81-2.84) | .20 | 1.38 (0.71-2.69) | .35 | ||
RV dysfunction [n=175] | 1.38 (0.72-2.66) | .33 | 0.95 (0.46-1.95) | .89 | ||
RVSP, per 5 units [n=101] | 1.56 (1.22-1.99) | <.001 | 1.52 (1.16-1.99) | .002 | 1.32 (1.03-1.69) | .03 |
RVSP ≥35 mm Hg [n=101] | 4.06 (1.65-9.97) | .002 | 3.14 (1.18-8.34) | .02 |
RV, right ventricular; RWMSI, regional wall motion score index; RVSP, right ventricular systolic pressure.
Troponin levels imputed using median in adjustment model. Model also includes indicator variable for imputation.
Troponin, RVSP, and D-dimer values imputed using median in model. Model also includes indicator variables for imputation.