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. 2021 Jan 19;96(4):932–942. doi: 10.1016/j.mayocp.2021.01.006

Table 4.

Association Between Selected Risk Factors and Death or Prolonged Hospitalization (N=70 events)a

Risk Factor Age Adjusted
Age- & Troponin-Adjusted Modelb
Multivariable Modelc
Area Under the Curve = 0.81 (0.74-0.88)
Odds Ratio (95% CI) P Odds Ratio (95% CI) P Odds Ratio (95% CI) P
Age, per 5 y 1.06 (0.97-1.16) .20 0.99 (0.90-1.10) .91 0.92 (0.81-1.03) .16
Nonwhite/non-Hispanic 1.49 (0.79-2.81) .22 1.29 (0.66-2.52) .46
Cancer 3.74 (0.93-15.06) .06 4.65 (1.10-19.48) .04
Cardiovascular disease 2.18 (0.95-4.99) .07 1.85 (0.77-4.44) .17 3.12 (1.20-8.17) .02
Atrial fibrillation/flutter [n=178] 1.60 (0.53-4.86) .40 1.53 (0.46-5.09) .49
Creatinine, per 1 SD [n=159] 1.77 (1.14-2.75) .01 1.40 (0.89-2.19) .14
Troponin, per 1 SD [n=133] 2.28 (1.36-3.80) .002 1.86 (1.16-2.98) .01
N-terminal prohormone B-type natriuretic peptide, per 1 SD [n=113] 2.85 (1.71-4.76) <.001 2.53 (1.46-4.39) .001
D-Dimer, per 1 SD 2.41 (1.60-3.65) <.001 2.30 (1.52-3.49) <.001 2.45 (1.59-3.76) <.001
Systolic blood pressure, per 5 mm Hg [n=178] 0.94 (0.87-1.01) .10 0.95 (0.88-1.03) .20
Diastolic blood pressure, per 5 mm Hg [n=177] 0.85 (0.75-0.97) .007 0.85 (0.75-0.97) .01
Ejection fraction, per 5% 0.92 (0.80-1.05) .23 0.99 (0.85,1.15) .88
RWMSI >1 [n=154] 2.95 (1.21-7.17) .02 1.66 (0.61-4.52) .32
RV enlargement [n=175] 1.51 (0.81-2.84) .20 1.38 (0.71-2.69) .35
RV dysfunction [n=175] 1.38 (0.72-2.66) .33 0.95 (0.46-1.95) .89
RVSP, per 5 units [n=101] 1.56 (1.22-1.99) <.001 1.52 (1.16-1.99) .002 1.32 (1.03-1.69) .03
RVSP ≥35 mm Hg [n=101] 4.06 (1.65-9.97) .002 3.14 (1.18-8.34) .02
a

RV, right ventricular; RWMSI, regional wall motion score index; RVSP, right ventricular systolic pressure.

b

Troponin levels imputed using median in adjustment model. Model also includes indicator variable for imputation.

c

Troponin, RVSP, and D-dimer values imputed using median in model. Model also includes indicator variables for imputation.