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. 2020 Jun 4;24(1):54–63. doi: 10.1093/ijnp/pyaa040

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© The Author(s) 2020. Published by Oxford University Press on behalf of CINP.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 4. — Higher number and activity of orexin-expressing cells in female rats. Immunohistochemical studies revealed that female rats had a higher number of orexin-expressing neurons across the dorsomedial hypothalamus/perifornical (DMH/PF) and lateral hypothalamus (LH) of the hypothalamus compared with males (a). Females also had an increased percentage of orexin cells that expressed cFos in the hypothalamus compared with males (b). Representative micrographs (40×) for males and females are presented (c). Orexin label is brown, cFos is black. Scale bar = 50 μm. *P < .05.