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. 2020 Dec 15;8(2):2002484. doi: 10.1002/advs.202002484

Figure 2.

Figure 2

Classification and domain architecture of the host DUB family. The host DUB family can be divided into six families of cysteine proteases, namely ubiquitin‐specific proteases (USPs), ovarian tumor proteases (OTUs), ubiquitin C‐terminal hydrolases (UCHs), the Josephin family, the motif interacting with ubiquitin (MIU)‐containing novel DUB family (MINDYs), zinc finger with UFM1‐specific peptidase domain protein/C6orf113/ZUP1 (ZUFSP), and one family of metalloprotease group, namely the JAB1/MPN/MOV34 metalloenzyme family (JAMMs, also known as MPN+). The conserved and specific domains are indicated by different shapes and colors.