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In vivo side effects evaluation. A) Body weight curves of mice in different drug groups during the experimental period. B) Hepatic (ALT and AST) and renal (UREA and CREA) function of nude mice after the last drug administration. All data were from three repeats. C) Histological analysis of major organs (heart, liver, spleen, lung, and kidney) from nude mice (Scale bar: 200 µm).
