Table IV.
Age-adjusted ORs and 95% CIs of COVID-19 severity and systemic symptoms by skin phenotype in patients with COVID-19–associated skin manifestations (n = 187)∗
| Cutaneous phenotypes | Moderate/severe COVID-19 |
Fever |
Cough |
Dyspnea |
Pneumonia |
Hyposmia/hypogeusia |
Gastrointestinal symptoms |
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | |
| Urticarial rash | 1.24 (0.43-3.62) | .6938 | 2.69 (0.72-10.10) | .1418 | 1.036 0.394 2.723 | .9433 | 1.78 (0.63-5.02) | .2781 | 1.351 0.4673.906 | .579 | 2.23 (0.81-6.12) | .1196 | 6.10 (2.25-16.59) | .0004 |
| Confluent erythematous/maculopapular/morbilliform rash | 1.9 (0.83-4.37) | .1307 | 0.83 (0.37-1.87) | .6462 | 2.25 (1.1-4.63) | .0269 | 2.05 (0.99-4.24) | .0519 | 1.5 (0.7-3.3) | .3121 | 0.67 (0.28-1.59) | .3632 | 0.82 (0.37-1.85) | .6391 |
| Papulovesicular exanthem | 1.44 (0.55-3.79) | .4565 | 2.44 (0.77-7.71) | .1283 | 0.96 (0.42-2.16) | .9185 | 0.71 (0.29-1.74) | .4507 | 1.34 (0.53-3.41) | .5387 | 1.83 (0.76-4.41) | .1814 | 0.65 (0.23-1.82) | .4154 |
| Chilblain-like acral pattern | 0.23 (0.09-0.55) | .0009 | 0.21 (0.1-0.46) | .0001 | 0.28 (0.13-0.6) | .001 | 0.2 (0.07-0.56) | .0024 | 0.29 (0.12-0.70) | .0063 | 0.19 (0.06-0.61) | .0054 | 0.51 (0.2-1.30) | .1579 |
| Livedo reticularis/racemosa-like and purpuric vasculitic pattern | 1.05 (0.25-4.39) | .9462 | 1.18 (0.24-5.85) | .8382 | 1.5 (0.43-5.18) | .5223 | 4.17 (1.05-16.5) | .0420 | 0.6 (0.17-2.16) | .4302 | 1.19 (0.30-4.64) | .8054 | 0.25 (0.03-1.97) | .1864 |
CI, Confidence interval; OR, odds ratio.
∗
Patients with more than 1 cutaneous phenotype were excluded from the statistical analysis.