Table 1. Baseline characteristics of cohort members (Covid-19 cases and related controls), individual (one by one, univariate) Odds Ratio (OR), and 90% Confidence Intervals (CI), for the relationship between selected diseases/conditions and the risk of SARS-CoV-2 infection.
| Cases (N = 3,497) | Controls (N = 17,358) | Individual OR (90% CI) | |
|---|---|---|---|
| Male gender | 1,945 (55.6%) | 9,640 (55.5%) | MV |
| Age (years) | |||
| 30–64 | 2,375 (67.9%) | 11,829 (68.1%) | MV |
| ≥65 | 1,122 (32.1%) | 5,538 (31.9%) | |
| Infectious and parasitic diseases | |||
| HIV infection | 68 (1.9%) | 301 (1.7%) | 1.12 (0.90 to 1.41) |
| Neoplasms | |||
| Malignant neoplasms | 155 (4.4%) | 661 (3.8%) | 1.18 (1.01 to 1.37) |
| Endocrine, nutritional and metabolic diseases, and immunity disorders | |||
| Thyroid disorders | 225 (6.4%) | 920 (5.3%) | 1.25 (1.10 to 1.42) |
| Diabetes | 411 (11.8%) | 1732 (10%) | 1.22 (1.10 to 1.35) |
| Hyperlipidaemia | 729 (20.8%) | 3708 (21.4%) | 0.97 (0.89 to 1.05) |
| Obesity | 48 (1.4%) | 153 (0.9%) | 1.58 (1.20 to 2.08) |
| Hyperuricemia/Gout | 180 (5.1%) | 711 (4.1%) | 1.28 (1.11 to 1.48) |
| Diseases of the blood and blood-forming organs | |||
| Anaemias | 265 (7.6%) | 927 (5.3%) | 1.48 (1.31 to 1.67) |
| Mental disorders | |||
| Dementia / Alzheimer | 48 (1.4%) | 89 (0.5%) | 2.79 (2.06 to 3.79) |
| Psychosis | 124 (3.5%) | 303 (1.7%) | 2.10 (1.75 to 2.52) |
| Depression | 233 (6.7%) | 1,003 (5.8%) | 1.17 (1.03 to 1.33) |
| Anxiety | 1,369 (39.1%) | 5,615 (32.3%) | 1.37 (1.29 to 1.47) |
| Diseases of the nervous system and sense organs | |||
| Parkinson’s disease | 67 (1.9%) | 188 (1.1%) | 1.78 (1.40 to 2.26) |
| Epilepsy | 176 (5%) | 660 (3.8%) | 1.35 (1.17 to 1.55) |
| Glaucoma | 119 (3.4%) | 482 (2.8%) | 1.25 (1.05 to 1.48) |
| Diseases of the circulatory system | |||
| Ischaemic Heart Disease/Angina | 213 (6.1%) | 841 (4.8%) | 1.29 (1.12 to 1.47) |
| Heart failure | 281 (8%) | 1,005 (5.8%) | 1.49 (1.31 to 1.69) |
| Arrhythmia | 196 (5.6%) | 738 (4.3%) | 1.36 (1.18 to 1.57) |
| Valvular diseases | 43 (1.2%) | 180 (1%) | 1.18 (0.88 to 1.57) |
| Vascular diseases | 52 (1.5%) | 186 (1.1%) | 1.41 (1.08 to 1.84) |
| Cerebrovascular diseases | 127 (3.6%) | 445 (2.6%) | 1.46 (1.22 to 1.74) |
| Hypertension | 826 (23.6%) | 3,731 (21.5%) | 1.15 (1.07 to 1.25) |
| Diseases of the respiratory system | |||
| Chronic respiratory diseases (COPD and asthma together) | 244 (7%) | 908 (5.2%) | 1.37 (1.21 to 1.56) |
| Diseases of the digestive system | |||
| Liver cirrhosis and other liver chronic diseases | 54 (1.5%) | 216 (1.2%) | 1.23 (0.96 to 1.59) |
| Inflammatory bowel diseases | 54 (1.5%) | 169 (1%) | 1.60 (1.23 to 2.07) |
| Diseases of the genitourinary system | |||
| Kidney disease with or without dialysis | 67 (1.9%) | 210 (1.2%) | 1.60 (1.26 to 2.03) |
| Diseases of the skin and subcutaneous tissues | |||
| Psoriasis | 23 (0.7%) | 113 (0.7%) | 1.02 (0.70 to 1.48) |
| Diseases of the musculoskeletal system and connective tissue | |||
| Rheumatologic conditions | 28 (0.8%) | 79 (0.5%) | 1.77 (1.23 to 2.56) |
| Other conditions | |||
| Transplantation | 13 (0.4%) | 59 (0.3%) | 1.10 (0.66 to 1.82) |
| Chronic pain | 89 (2.5%) | 378 (2.2%) | 1.19 (0.97 to 1.45) |
| Inflammation, not elsewhere specified | 410 (11.7%) | 2,244 (12.9%) | 0.89 (0.81 to 0.98) |
Abbreviation: MV, matching variable.