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. 2021 Jan 20;16(1):e0237202. doi: 10.1371/journal.pone.0237202

Table 2. Independent (all together, multivariate) Odds Ratio (OR), and 90% Confidence Intervals (CI), for the relationship between selected diseases/conditions and the risk of SARS-CoV-2 infection as a whole (3,497 cases and corresponding 17,358 controls), as well as the risk of fatal SARS-CoV-2 infection (435 cases and corresponding 2,154 controls).

All Covid-19 cases Fatal Covid-19 cases
Cases / Controls OR (90% CI) Cases / Controls OR (90% CI)
Infectious and parasitic diseases
    HIV infection 68 / 301 1.07 (0.85 to 1.34) 11 / 47 1.04 (0.58 to 1.86)
Neoplasms
    Malignant neoplasms 155 / 661 0.99 (0.85 to 1.16) 35 / 147 0.99 (0.70 to 1.42)
Endocrine, nutritional and metabolic diseases, and immunity disorders
    Thyroid disorders 225 / 920 1.13 (0.99 to 1.29) 31 / 133 0.93 (0.64 to 1.37)
    Diabetes 411 / 1,732 1.15 (1.03 to 1.28) 88 / 327 1.30 (1.01 to 1.67)
    Hyperlipidaemia 729 / 3,708 0.86 (0.79 to 0.94) 131 / 703 0.69 (0.55 to 0.86)
    Obesity 48 / 153 1.18 (0.89 to 1.57) 6 / 18 1.08 (0.46 to 2.56)
    Hyperuricemia/Gout 180 / 711 1.08 (0.93 to 1.27) 56 / 175 1.29 (0.95 to 1.76)
Diseases of the blood and blood-forming organs
    Anaemias 265 / 927 1.24 (1.09 to 1.41) 63 / 184 1.45 (1.07 to 1.95)
Mental disorders
    Dementia / Alzheimer 48 / 89 2.14 (1.55 to 2.96) 14 / 27 1.92 (1.02 to 3.63)
    Psychosis 124 / 303 1.71 (1.40 to 2.08) 35 / 57 2.68 (1.76 to 4.08)
    Depression 233 / 1,003 0.98 (0.86 to 1.12) 49 / 149 1.21 (0.88 to 1.67)
    Anxiety 1,369 / 5,615 1.26 (1.17 to 1.36) 217 7,824 1.33 (1.07 to 1.65)
Diseases of the nervous system and sense organs
    Parkinson’s disease 67 / 188 1.32 (1.02 to 1.70) 18 / 47 1.32 (0.80 to 2.18)
    Epilepsy 176 / 660 1.10 (0.94 to 1.28) 44 / 99 1.57 (1.11 to 2.22)
    Glaucoma 119 / 482 1.22 (1.03 to 1.46) 27 / 95 1.32 (0.89 to 1.97)
Diseases of the circulatory system
    Ischaemic Heart Disease/Angina 213 / 841 0.99 (0.84 to 1.15) 58 / 186 1.24 (0.88 to 1.76)
    Heart failure 281 / 1,005 1.24 (1.07 to 1.44) 86 / 268 1.41 (1.04 to 1.90)
    Arrhythmia 196 / 738 1.14 (0.98 to 1.33) 51 / 198 0.95 (0.68 to 1.31)
    Valvular diseases 43 / 180 0.80 (0.59 to 1.09) 11 / 42 0.84 (0.44 to 1.60)
    Vascular diseases 52 / 186 1.00 (0.75 to 1.32) 9 / 40 0.69 (0.36 to 1.33)
    Cerebrovascular diseases 127 / 445 1.00 (0.83 to 1.21) 37 / 108 1.06 (0.72 to 1.56)
    Hypertension 826 / 3,731 1.12 (1.01 to 1.24) 167 / 712 1.16 (0.94 to 1.43)
Diseases of the respiratory system
    Chronic respiratory diseases (COPD and asthma together) 244 / 908 1.18 (1.03 to 1.35) 50 / 178 1.14 (0.83 to 1.55)
Diseases of the digestive system
    Liver cirrhosis and other liver chronic diseases 54 / 216 0.93 (0.71 to 1.21) 14 / 35 1.42 (0.79 to 2.56)
    Inflammatory bowel diseases 54 / 169 1.47 (1.13 to 1.91) 6 / 32 0.72 (0.33 to 1.56)
Diseases of the genitourinary system
    Kidney disease with or without dialysis 67 / 210 1.10 (0.84 to 1.42) 23 / 60 1.07 (0.60 to 1.90)
Diseases of the skin and subcutaneous tissues
    Psoriasis 23 / 113 0.93 (0.63 to 1.36) 2 / 19 0.39 (0.11 to 1.44)
Diseases of the musculoskeletal system and connective tissue
    Rheumatologic conditions 28 / 79 1.54 (1.06 to 2.23) 5 / 18 1.21 (0.50 to 2.91)
Other conditions
    Transplantation 13 / 59 0.87 (0.52 to 1.46) 3 / 8 1.45 (0.42 to 4.97)
    Chronic pain 89 / 378 1.06 (0.86 to 1.31) 21 / 78 1.08 (0.69 to 1.70)
    Inflammation, not elsewhere specified 410 / 2,244 0.85 (0.77 to 0.93) 74 / 316 1.12 (0.87 to 1.45)