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. 2021 Jan 7;17(1):e1008569. doi: 10.1371/journal.pcbi.1008569

Fig 5. Differentially expressed genes (DEGs) between bulk and single cell data.

Fig 5

Top panel is the delta AUROC for single-cell DEGs ordered by adjusted p-value for each separate deletion strain. Bottom panel is the delta Jaccard index between bulk DEGs and single cell DEGs at FDR = 0.01. Preprocessed is count normalized and log-transformed with no denoising method. Delta is taken between denoised and preprocessed. All computed metrics can be found in S2 Table.