Table 3. First documented supraventricular tachycardia in isolated pre-capillary pulmonary hypertension.
| Clinical classification of PH | Total n = 641 | Group 1 PH | Group 3 PH | Group 4 PH | Group 5 PH | P value | ||
|---|---|---|---|---|---|---|---|---|
| PAH Idiopathic/heritable n = 220 | PAH associated with CTD n = 62 | PAH associated with CHD n = 52 | Lung disease/hypoxia n = 140 | CTEPH No PEA n = 130 | Unclear/Multifactorial n = 37 | |||
| No of patients with SVT | 162 (25%) | 54 (25%) | 18 (29%) | 18 (35%) | 23 (16%) | 39 (30%) | 10 (27%) | 0.01 |
| Typical AFL | 28 (4.4%) | 12 (5.5%) | 2 (3.2%) | 3 (5.8%) | 1 (0.7%) | 8 (6.2%) | 2 (5.4%) | NS |
| AF total | 110 (17%) | 34 (16%) | 16 (26%) | 9 (17%) | 20 (14%) | 25 (19%) | 6 (16%) | 0.01 |
| AF paroxysmal | 49 (7.6%) | 9 (4.0%) | 10 (16%) | 4 (7.7%) | 11 (7.8%) | 13 (10%) | 2 (5.4%) | NS |
| AF persistent | 23 (3.6%) | 9 (4.0%) | 2 (3.2%) | 2 (3.8%) | 1 (0.7%) | 6 (4.6%) | 3 (8.1%) | NS |
| AF permanent | 38 (5.9%) | 16 (7.3%) | 4 (6.4%) | 3 (5.8%) | 8 (5.7%) | 6 (4.6%) | 1 (2.7%) | NS |
| AVNRT | 4 (0.6%) | 1 (0.5%) | 0 | 1 (1.9%) | 0 | 1 (0.8%) | 1 (2.7%) | NS |
| AVRT | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| Focal AT | 1 (0.2%) | 0 | 0 | 1 (1.9%) | 0 | 0 | 0 | - |
| Other AT | 19 (3.0%) | 7 (3.2%) | 0 | 4 (7.7%) | 2 (1.4%) | 5 (3.8%) | 1 (2.7%) | NS |
| Proportion of patients with SVT onset prior to diagnosis of PH | 51 (8.0%) | 13 (5.9%) | 8 (13%) | 5 (9.6%) | 7 (5%) | 14 (11%) | 4 (11%) | NS |
| -at diagnosis of SVT and PH | 49 (7.6%) | 14 (6.4%) | 6 (9.7%) | 6 (12%) | 6 (4.3%) | 14 (11%) | 3 (8.1%) | NS |
| - after diagnosis of PH | 62 (9.7%) | 27 (12%) | 4 (6.5%) | 7 (13%) | 10 (7.1%) | 11 (8.5%) | 3 (8.1%) | NS |
Values are expressed as n (%). P-value shows differences among major classes. NS–non-significant. PH–pulmonary hypertension; PAH–pulmonary arterial hypertension; CTD–connective tissue disease; CHD–congenital heart disease; CTEPH–chronic thrombembolic pulmonary hypertension; AFL–atrial flutter; AF–atrial fibrillation; AVNRT–atrio-ventricular nodal reentry tachycardia; AVRT–atrio-ventricular reentry tachycardia; AT–atrial tachycardia.