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. 2021 Jan 20;16(1):e0245752. doi: 10.1371/journal.pone.0245752

Table 4. Clinical outcome.

Univariate analysis Multivariate Cox regression analysis
Dead NO N = 340 Dead YES N = 415 p RR 95% CI p
Prevalent SVT 93 (27%) 127 (31%) NS - - -
Prevalence AF 66 (19%) 93 (22%) NS - - -
Age < 60 years 171 (50%) 132 (32%) <0.001 0.49 0.38–0.65 <0.001
Male gender 118 (35%) 191 (46%) 0.002 1.48 1.18–1.87 <0.001
Arterial hypertension 191 (56%) 243 (59%) NS - - -
Diabetes mellitus 89 (26%) 126 (30%) NS - - -
Stroke or Systemic embolism 23 (7%) 33 (8%) NS - - -
NYHA III or IV classes 225 (66%) 382 (92%) <0.001 1.77 1.19–2.65 0.005
6MWT < 350 m 119 (35%) 255 (61%) <0.001 1.88 1.42–2.49 <0.001
RAP < 10 mm Hg 188 (55%) 179 (43%) 0.001 1.02 0.80–1.29 0.54
PAMP < 50 mm Hg 214 (63%) 238 (57%) NS - - -
LA diameter < 40 mm 164 (48%) 167 (40%) NS - - -
RA diameter < 48 mm 221 (65%) 179 (43%) <0.001 0.67 0.54–0.86 0.001
Cpc-PH 40 (12%) 74 (18%) 0.023 1.22 0.90–1.66 0.20

Values are expressed as n (%). NS–non-significant. SVT–supraventricular tachycardia; AF–atrial fibrillation; SR–sinus rhythm; 6MWT–six-minute walking test; RAP–right atrial pressure; PAMP–pulmonary arterial mean pressure; LA–left atrium; RA–right atrium. Cpc-PH–combined post- and pre-capillary pulmonary hypertension.