Table 3.
CTX (n = 64) | PCN G (n = 30) | P Value | |
---|---|---|---|
Primary end point | |||
Composite safety end point | 9 (14.1) | 8 (26.7) | .139 |
Secondary end points | |||
Composite safety end point components | |||
At least 1 readmission due to VGS or therapy | 7 (10.9) | 6 (20) | .336 |
Microbiological evidence of ESBL | 1 (1.6) | 1 (3) | .539 |
C. difficile infection | 1 (1.6) | 1 (3) | .539 |
Therapy modification or discontinuation due to adverse drug event | 0 (0) | 0 (0) | .549 |
Infection recurrence | 0 (0) | 0 (0) | N/A |
Hospital readmission | |||
At least 1 readmission in 6 mo | 24 (37.5) | 16 (53) | .148 |
No. of readmissions, median (IQR), d | 0 (0–1) | 1 (0–1.25) | .341 |
Time to first readmission, median (IQR), d | 31 (15–60) | 53 (29–91) | .135 |
All-cause mortality | 0 (0) | 2 (7) | .100 |
All data expressed as No. (%) unless otherwise noted.
Abbreviations: CTX, ceftriaxone; ESBL, extended-spectrum beta-lactamase; IQR, interquartile range; PCN G, penicillin G; VGS, viridans group streptococci.