Table 1.

Pathways enriched in IFN-γ–activated and unactivated ΔUfc1 cells

Pathway enrichment	FDR q-value
Pathway enrichment in IFN-γ–activated ΔUfc1 cells
HALLMARK_TNFA_SIGNALING_VIA_NFKB	0
HALLMARK_INFLAMMATORY_RESPONSE	0
KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION	0
GO_POSITIVE_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY	0.03
GO_NEGATIVE_REGULATION_OF_ADAPTIVE_IMMUNE_RESPONSE	0.04
GO_NEGATIVE_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS	0.04
GO_T_CELL_MEDIATED_IMMUNITY	0.04
GO_PEPTIDE_TRANSPORT	0.04
Pathway enrichment in unactivated ΔUfc1 cells
KEGG_PROTEIN_EXPORT	0
GO_ROUGH_ENDOPLASMIC_RETICULUM	0.01
GO_INTRAMOLECULAR_OXIDOREDUCTASE_ACTIVITY_TRANSPOSING_S_S_BONDS	0.01
GO_IRE1_MEDIATED_UNFOLDED_PROTEIN_RESPONSE	0.01
GO_ENDOPLASMIC_RETICULUM_GOLGI_INTERMEDIATE_COMPARTMENT_MEMBRANE	0.03
GO_PROTEIN_EXIT_FROM_ENDOPLASMIC_RETICULUM	0.03
GO_ENDOPLASMIC_RETICULUM_GOLGI_INTERMEDIATE_COMPARTMENT	0.03
GO_ENDOPLASMIC_RETICULUM_LUMEN	0.03
GO_PEPTIDYL_ASPARAGINE_MODIFICATION	0.03
REACTOME_COLLAGEN_FORMATION	0.03
GO_ROUGH_ENDOPLASMIC_RETICULUM_MEMBRANE	0.04
REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION	0.04

GSEA for GO terms, KEGG, Reactome, and Hallmark pathways. Only pathways with FDR q-value < 0.05 are shown. See also Dataset S4.