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. 2020 Dec 21;118(1):e2012339118. doi: 10.1073/pnas.2012339118

Table 2.

Drug list

Chemical names Abbreviations Doses Targets Providers, catalog no.
Tetrodotoxin TTX 0.5 µM Na+ channel blocker Tocris, 1069 and Cayman, 14964
Kisspeptin-10 KP 10 or 100 nM Kiss1r agonist Tocris, 4243 and Phoenix Pharmaceuticals Inc., 048–56
Okadaic acid OKA 30 nM Protein phosphatase 1 and 2A inhibitor Cayman, 10011490
N-acetoyl-D-erythro-sphingosine C2 ceramide 20 µM Protein phosphatase A2 activator Cayman, 62510
Bisindolylmaleimide X BIM X 100 nM Protein kinase C inhibitor Cayman, 17511
2-Aminoethoxydi-phenylborane 2-APB 75 µM TRPC1, TRPC3, TRPC5, and TRPC6 blocker & IP3 receptor blocker Cayman, 64970
Nifedipine Nif 1 µM L-type voltage-gated calcium channel blocker Sigma, N7634
ω-conotoxin GVIA Ctx GVIA 100 nM N-type voltage-gated calcium channel blocker Sigma, C9915
SKF96365 SKF96365 30 µM TRPC6, TRPC7 blocker Tocris, 1147
Lanthanum La3+ 100 µM TRPC3, TRPC4/5, TRPC6, TRPC7 blocker Sigma, 449830
Flufenamic acid FFA 100 µM TRPC3, TRPC5, and TRPC7 inhibitor Sigma, F9005
Wortmannin Wort [nM] 100 nM PI3K inhibitor Cayman 10010591
Wortmannin Wort [µM] 10 µM PI4K inhibitor
Diethylamine NONOate DEA/NO 100 µM NO donor Cayman 82100
8-pCPT-cGMP cGMP 200 µM GMP-dependent protein kinase activator Sigma, C5438
1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one ODQ 30 µM NO-sensitive guanylyl cyclase inhibitor Cayman, 81410
Y27632 Y27632 10 µM ROCK-I and ROCK-II inhibitor MedChemExpress, HY-10583