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. 2020 Dec 21;118(1):e2008072118. doi: 10.1073/pnas.2008072118

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Fig. 3. — 6QC-ICG highlights adenomas during endoscopic surveillance in Apc^Pirc/+ rats. (A) Polyps (arrowheads) in the colon of an Apc^Pirc/+ rat are highlighted by 6QC-ICG during WL/NIRF endoscopy. (B) Wide-field NIRF imaging system of freshly resected colorectal tissue of an Apc^Pirc/+ rat injected with 6QC-ICG. White lines and roman numerals indicate regions sampled for histology in C. (C) H&E histology, NIRF, and CD68 stain images of corresponding tissue sections (B, lesions I to III). The square indicates the location used for the higher-magnification (10×) microscopy images (Bottom).