Table 3.
Clinical data of non-AKI and AKI subgroups in the MCD patients.
| Items | Non-AKI(n = 257) | AKI(n = 109) | Statistical values | P |
| Age (years), median (Q1, Q3) | 28 (20, 44) | 43 (27, 59) | 5.487∗ | <0.001 |
| Male, n (%) | 132 (51.4) | 85 (78.0) | 22.470† | <0.001 |
| Alanine aminotransferase (U/L), median (Q1, Q3) | 19.0 (13.2, 34.0) | 18.7 (12.3, 32.6) | 0.380∗ | 0.704 |
| Aspartate aminotransferase (U/L), median (Q1, Q3) | 19.2 (15.0, 26.0) | 19.3 (14.7, 31.5) | 1.058∗ | 0.290 |
| γ-glutamyl transpeptidase (U/L), median (Q1, Q3) | 25.5 (16.2, 39.1) | 29.2 (18.7, 52.5) | 1.294∗ | 0.122 |
| Serum creatinine (μmol/L), median (Q1, Q3) | 69.7 (57.7, 81.9) | 129.5 (105.7, 171.1) | 14.190∗ | <0.001 |
| Serum urea (mmol/L), median (Q1, Q3) | 4.7 (3.6, 6.4) | 10.1 (6.2, 15.8) | 10.545∗ | <0.001 |
| Total protein (g/L), mean ± SD | 46.2 ± 4.7 | 43.6 ± 8.7 | 0.848‡ | 0.397 |
| Serum albumin (g/L), mean ± SD | 21.5 ± 5.7 | 19.9 ± 6.1 | 2.376‡ | 0.018 |
| 24 h urine protein (g/d), mean ± SD | 5.6 (4.4, 8.1) | 5.9 (4.6, 8.4) | 1.236‡ | 0.216 |
| Immunoglobulin E (IU/mL), median (Q1, Q3) | 142.0 (35.3, 516.5) | 266.0 (86.7, 963.0) | 2.742∗ | 0.007 |
| History of diabetes, n (%) | 3 (1.2) | 7 (6.4) | – | 0.009 |
| History of hypertension, n (%) | 13 (5.1) | 26 (23.9) | 28.238† | <0.001 |
| Chronic renal interstitial lesion, n (%) | 7 (2.7) | 5 (4.6) | – | 0.268 |
| Intrarenal arteriosclerosis, n (%) | 4 (1.6) | 3 (2.8) | – | 0.347 |
∗
Z values.
†
χ2 values.
‡
t values.
AKI: Acute kidney injury; MCD: Minimal change disease; SD: Standard deviation; -: Not available.