Table 3. Characteristics of NAFLD patients according to microbiota diversity index (OTU, Shannon-Weaver Index, and Simpson’s Diversity Index).

	OTU	p value	Shannon-Weaver Index	P value	Simpson Diversity Index	p value
Fibrosis
Non Significant	155 (90–331)	0.141	3.94 (1.63–5.43)	0.245	0.88 (0.38–0.95)	0.473
Significant	190 (101–296)		4.39 (2.93–5.59)		0.90 (0.76–0.96)
Steatosis
Non Significant	155 (93–331)	0.808	3.94 (1.63–5.33)	0.447	0.86 (0.38–0.95)	0.213
Significant	177 (90–269)		4.22 (2.58–5.59)		0.90 (0.75–0.96)
BMI
Non Obese	177 (99–331)	0.527	4.45 (1.63–5.43)	0.183	0.91 (0.38–0.95)	0.080
Obese	176 (90–296)		3.92 (2.31–5.59)		0.87 (0.60–0.96)
Central obesity
No	192 (155–214)	0.404	4.54 (4.06–4.98)	0.221	0.91 (0.88–0.94)	0.266
Yes	176 (90–331)		4.11 (1.63–6.59)		0.88 (0.38–0.96)
Triglyceride
Normal	183 (101–331)	0.010*	4.33 (3.06–5.59)	0.005*	0.91 (0.76–0.96)	0.003*
Increase	118 (90–201)		3.68 (1.63–4.41)		0.83 (0.38–0.90)
HDL
Normal	188 (97–296)	0.158	4.38 (1.63–5.59)	0.064	0.91 (0.38–0.96)	0.114
Decrease	151 (90–331)		3.84 (2.31–5.33)		0.87 (0.60–0.94)
LDL
Normal	169 (106–331)	0.929	4.15 (3.06–5.33)	0.546	0.90 (0.80–0.94)	0.339
Increase	180 (90–296)		4.14 (1.63–5.59)		0.88 (0.38–0.96)
Diabetes mellitus
No	181 (112–220)	0.684	4.06 (3.76–4.96)	0.816	0.88 (0.84–0.95)	0.485
Yes	172 (90–331)		4.18 (1.63–5.59)		0.88 (0.38–0.96)

Data are presented as medians (minimum-maximum). NAFLD: non-alcoholic fatty liver disease; OTU: operational taxonomic unit; BMI: body mass index; HLD: high-density lipoprotein; LDL: low-density lipoprotein. *Statistically significant by Mann-Whitney test.