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Mapping of residues of the main protease of SARS-CoV-2, which differ from SARS-CoV. Structure 6Y2E is depicted in ribbon form in grey, non-conserved residues are shown in stick form in magenta. Cleavage sequences at the N- and C-termini of the main protease (NSP5) are shown. (Sequence alignment and a complete list of cleavage sites are provided in the Supporting Information, as Fig. S1 and Table S1, respectively).
