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. 2020 Sep 18;34(2):417–425. doi: 10.1038/s41379-020-00671-z

Table 1.

Clinical background.

Total Group I
<1 year
Group II
1 < years < 2
Group III
>4 years
SVM model training patients
Cases 69 16 22 31
ROI HCC 1369 219 558 592
non-HCC 738 136 273 329
Total 2107 355 831 921
Nuclei HCC 979,086 130,178 413,665 435,243
Normal 328,463 57,437 120,702 150,324
Total 1,307,549 187,615 534,367 585,567
Gender M 48 11 16 21
F 21 5 6 10
Age Average 65.4 65.8 67.0 64.0
MAX 80 75 80 80
MIN 40 42 54 40
Virus HBV 19 5 6 8
HCV 36 8 13 15
NBNC 14 3 3 8
Background LC 34 8 11 15
CH 32 8 11 13
Normal 3 0 0 3
Size (mm) Average 27.8 28.3 26.5 28.4
MAX 48.0 48.0 43.0 47.0
MIN 9.0 20.0 9.0 10.0
Nodule Average 1.3 1.7 1.1 1.2
MAX 3 3 2 3
MIN 1 1 1 1
SVM model test patients
Cases 89 23 28 38
ROI HCC 1346 434 324 588
non-HCC 680 189 168 323
Total 2026 623 492 911
Nuclei HCC 886,900 317,855 185,672 383,373
Normal 251,376 66,243 59,148 125,985
Total 1,138,276 384,098 244,820 509,358
Gender M 67 17 23 27
F 22 6 5 11
Age Average 67.8 68.2 71.3 65.1
MAX 83 79 82 83
MIN 28 47 46 28
Virus HBV 12 2 0 10
HCV 53 16 17 20
NBNC 24 5 11 8
Background LC 53 16 14 23
CH 32 7 12 13
NON 4 0 2 2
Size (mm) Average 26.3 38.5 27.7 24.2
MAX 45.0 45.0 45.0 45.0
MIN 10.0 15.0 14.0 10.0
Nodule Average 1.3 1.7 1.4 1.1
MAX 3 3 3 2
MIN 1 1 1 1

HCC HCC area, non-HCC surrounding non-HCC area, ROI used ROI number, Nuclei calculated number of nuclei, NBNC neither HBV nor HCV infection.