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. 2021 Jan 7;10:591698. doi: 10.3389/fonc.2020.591698

Figure 2.

Figure 2

NUSAP1 is upregulated in GC and predicts disease progression and poor prognosis. (A, B) Analysis of the relative mRNA expression of NUSAP1 in the TCGA and GEPIA database (Student’s t test, *p<0.05). (C) The expression profile of NUSAP1 in GC and normal tissues was searched in the Oncomine Gene Browser (Student’s t test, p<0.05). (D) Representative images of IHC staining of NUSAP1 in human GC tissues and non-neoplastic tissue samples. Scale bars represent 50 μM or 25 μM. (E) The correlation between NUSAP1 expression and overall survival in patients with GC obtained from Kaplan–Meier Plotter databases (log-rank test, p<0.01). (F) The correlation between NUSAP1 expression and relapse-free survival (RFS) in patients with GC obtained from Kaplan–Meier Plotter databases (log-rank test, p<0.01). (G) Kaplan–Meier survival analysis performed with survival data of gastric patients with high NUSAP1 expression (n=90) versus low NUSAP1 expression (n=71), Log-rank test, p=0.012.