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. 2021 Jan 7;10:591698. doi: 10.3389/fonc.2020.591698

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Copyright © 2021 Guo, Zou, Zhou, Zhong, He, Huang, Chen, Li, Xiong, Fang and Xiang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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NUSAP1 expression positively correlates with YAP1 protein levels in GC. (A) Western blotting analysis of NUSAP1 and YAP1 levels in GES-1, AGS, BGC823, MGC803, HGC-27, SGC7901, and MKN45 cell lines. GAPDH was used as a loading control. (B) Western blotting analysis of NUSAP1 levels in lysates prepared from 8 paired GC tissues and normal gastric tissues. (C) The correlation analysis of NUSAP1 and YAP1 expression levels in 8 GC patients. (D) Representative immunochemical staining of NUSAP1 and YAP1 in GC tissues. (E, F) Correlation of NUSAP1 expression with YAP1 expression in primary 48 GC patients (Pearson’s correlation coefficient, the chi-square test, p<0.01).