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. 2020 Nov 23;100(2):487–498. doi: 10.1007/s00277-020-04358-y

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — GSEA enrichment plots of HSC and LSC signatures and scatter plot of genes positively associated with higher KIAA0125 expression. a GSEA enrichment plots show positive association of higher KIAA0125 expression with HSC and LSC signatures curated from several published reports in both the NTUH and TCGA cohorts; b the scatter plot reveals the genes strongly correlated to KIAA0125 expression in both the NTUH and TCGA cohorts (pink). The correlation measurement is based on the Spearman’s correlation coefficient between the given gene and KIAA0125. The strongly correlated genes are defined as their correlation values at top 5% of all genes in both cohorts