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. 2020 Aug 25;147(2):579–591. doi: 10.1007/s00432-020-03361-0

Fig. 5.

Fig. 5

Kaplan–Meier plot for overall survival (OS) in patients with metastatic disease, which were not treated with antibiotics upon first-line palliative chemotherapy stratified for the Systemic Inflammation Score (SIS). Patients with a SIS of 0/1 had a median OS of 9.8 months and patients with a SIS of 2–4 had a median OS of only 4.4 months (p < 0.001, log rank)