Table 1. Patient Demographics and Genetic Profiles of the Tumors of 76 Patients.
| Parameter | No. of Tumors (Total = 76) |
|---|---|
| Sex (%) | |
| Male | 47 (61.8) |
| Female | 29 (38.1) |
| Mean age, years (range) | 47.69 (19–68) |
| Pathologic diagnosis (%) | |
| Anaplastic astrocytoma | 57 (75.0) |
| Anaplastic oligodendroglioma | 19 (25.0) |
| Mean follow up (in months) | 16.3 |
| Number of events (%) | 22 (28.9) |
| Genetic information (%) | |
| IDH mutation | |
| Mutant | 47 (61.8) |
| Wild type | 29 (38.1) |
| 1p/19q | |
| Codeletion | 19 (25.0) |
| No deletion | 57 (75.0) |
| ATRX | |
| Loss | 16 (42.1) |
| No loss | 22 (57.9) |
| NA | 40 (52.6) |
| MGMT promoter | |
| Methylated | 46 (60.5) |
| Unmethylated | 30 (39.5) |
| EGFR | |
| Amplified | 3 (4.1) |
| Non-amplified | 71 (95.9) |
| NA | 2 (2.6) |
EGFR = epidermal growth factor receptor, IDH = isocitrate dehydrogenase, MGMT = O6-alkylguanine DNA alkyltransferase, NA = not available, 1p/19q = chromosome arm 1p/19q