Table 4. Univariable and Multivariable Regression Analyses of Imaging Parameters and Genomic Profiles.
| Univariable Analysis | Multivariable Analysis | |||||||
|---|---|---|---|---|---|---|---|---|
| OR | P | OR | P | AUC | 95% CI | P for ROC | Cut-Off | |
| IDH mutation | ||||||||
| T2 volume | 1.01 | 0.035 | 1.01 | 0.139 | ||||
| CBF_mean | 0.45 | 0.058 | ||||||
| ADC_mean | 8.54 | 0.010 | 6.05 | 0.037 | 0.67 | 0.56–0.78 | 0.008 | > 1.49 |
| 1p/19q codeletion | ||||||||
| CBV_mean | 3.49 | 0.037 | 1418.81 | 0.022 | 0.68 | 0.53–0.81 | 0.035 | > 1.59 |
| CBV_85 | 2.22 | 0.059 | ||||||
| ADC_mean | 0.03 | 0.005 | 2.85 | 0.975 | ||||
| ADC_5 | 0.00 | 0.002 | 9.65 | 0.339 | ||||
| ADC_10 | 0.00 | 0.003 | 29.43 | 0.859 | ||||
| ADC_15 | 0.00 | 0.002 | 24.21 | 0.478 | ||||
AUC = area under curve, CI = confidence interval, Cut-off = cut-off values for the prediction of genomic profiles of World Health Organization grade III gliomas, OR = odds ratio, ROC = receiver operating curve