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. 2021 Jan 7;10:534095. doi: 10.3389/fonc.2020.534095

Figure 6.

Figure 6

Kremen2 knockdown repressed tumorigenicity of gastric cancer cells in vivo. Transfected GC cells expressing luciferase were subcutaneously injected to establish xenografts. Data including tumor volume and bodyweight were collected every two days. At the end of the in vivo study, bioluminescence was observed via an in vivo imaging system. (A) Tumor volume. (B) Body weight of nude mice. (C) In vivo imaging weight of tumor at the end of experiment (Day 28). (D) Tumors and tumor weight at the end of experiment. (E) H&E and Ki67 analysis of paraffin-embedded tumor tissues, and Ki67 expression score was calculated. **P < 0.01; ***P < 0.001. Scale bar is 50 μm.