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. 2021 Jan 20;4:93. doi: 10.1038/s42003-020-01577-x

Fig. 3. Non protease inhibitor ombitasvir inhibited SARS-CoV-2 3CLpro activity partially.

Fig. 3

The non-protease anti-viral drugs selected by computational studies were screened for their inhibitory activity against SARS-CoV-2 3CLpro enzyme as described under Methods section. The percent enzymatic activity was calculated as described in Fig. 1 legend. Blank values were subtracted from all the readings before calculating the percent activity. Representative of three individual experiments with triplicate values were presented graphically (n = 3). P value < 0.001 considered as statistically significant. One-way ANOVA with Dunnett’s Multiple Comparison post-hoc test used to calculate the statistical significance.