TABLE 3.

Results of 2-way ANOVA analyses.

		CTRL vs delay		LL-ad lib vs LL-RF
Gene	Two-way ANOVA	P value	P value summary	P value	P value summary
c-fos	Interaction	<0.0001	****	0.0022	**
	Time	<0.0001	****	0.0012	**
	Group	<0.0001	****	<0.0001	****
Per1	Interaction	0.0692	ns	0.0572	ns
	Time	0.4003	ns	0.1254	ns
	Group	<0.0001	****	<0.0001	****
Per2	Interaction	0.3168	ns	<0.0001	****
	Time	0.0205	*	<0.0001	****
	Group	<0.0001	****	0.0609	ns
Nr1d1	Interaction	0.1673	ns	<0.0001	****
	Time	0.8828	ns	0.0008	***
	Group	<0.0001	****	0.7785	ns
Rorα	Interaction	0.8877	ns	<0.0001	****
	Time	0.0072	**	0.0003	***
	Group	0.0226	*	0.4578	ns
Dbp	Interaction	0.4036	ns	0.0004	***
	Time	0.0666	ns	0.0002	***
	Group	<0.0001	****	0.0205	*
VIP	Interaction	0.0024	**	0.1359	ns
	Time	0.0006	***	<0.0001	****
	Group	0.0489	*	<0.0001	****
AVP	Interaction	0.0509	ns	0.0043	**
	Time	<0.0001	****	<0.0001	****
	Group	0.5173	ns	0.3543	ns
Nr3c1	Interaction	0.0488	*	0.6803	ns
	Time	0.2163	ns	0.0104	*
	Group	<0.0001	****	0.3721	ns

Comparison between the gene expression profiles in the fetal SCN of the control group (CTRL) and the group exposed to 6-h phase delay in LD12:12 (Delay), and between the group exposed to constant light with ad libitum feeding (LL-ad lib) and constant light with restricted feeding regime (LL-RF). The gene expression profiles are shown in Figures 2, 5. The results of significance levels (P) for the interaction between groups, the effect of time and the effect of group (gray) are shown.