REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
Rabbit monoclonal antibody MDR1/ABCB1 (E1Y7S)	Cell Signaling	#13978; RRID:AB_2798357
Rat monoclonal antibody BCRP/ABCG2 (BXP-53)	Abcam	Ab24115; RRID:AB_447879
Chemicals, peptides, and recombinant proteins
14C-aminoisobutyrate (AIB)	Tjaden Biosciences, Burlington, IA, USA	N/A
Dextran, Fluorescein, 3,000 MW Anionic	Invitrogen/ Thermo	D3305
Dextran, Fluorescein, 10,000 MW Anionic	Invitrogen/ Thermo	D1821
Sulforhodamine 101 (TexasRed)	Invitrogen/ Thermo	11570676
Paclitaxel (Taxol©)	Bristol Myers Squibb	N/A
Docetaxel	Hospira, UK	N/A
Temozolomide	Schering Plough	N/A
Neuro-basal medium	Thermo Fisher	10888022
DMEM/F12 Glutamax	Thermo Fisher	10565018
B-27 Supplement (50x), minus vitamin A	Thermo Fisher	12587010
Recombinant Human Epidermal Growth Factor (rEGF)	Peprotech	#AF100-15
Recombinant Human Fibroblast Growth Factor (rFGFb)	Peprotech	#100-18B
Minimum essential medium (MEM	Thermo Fisher	31095052
L-glutamine	Thermo Fisher s	25030024
Sodium pyruvate	Thermo Fisher	11360039
Vitamins	Thermo Fisher	11120-037
Penicillin / Streptomycin	Thermo Fisher	15140122
Non-essential amino acids	Thermo Fisher	11140035
Fetal Calf serum	Thermo Fisher	10500064
Gadoterate meglumine (Dotarem®)	Guerbet; Villepinte, France	N/A
D-luciferin	Promega, Madison, WI, USA	E1605
Trypsin-EDTA	Thermo Fisher	25300054
Experimental models: cell lines
Mel57, Mel57VEGF	Dr W.P. Leenders, (Radboud UMC, Nijmegen, NL)	RRID:CVCL_4454
GBM8	Bakhos Tannous (MGH, Boston, USA)	N/A
U87	ATCC, Manassas, VA, USA	RRID: CVCL_0022
RG2	ATCC, Manassas, VA, USA	RRID: CVCL_3581
Experimental models: organisms/strains
Mouse: Friends Virus B (FVB) nude	NKI animal facility	N/A
Mouse: Abcb1a/b−/− FVB nude	NKI animal facility	N/A
Mouse: Abcg2−/−;Abcb1a/b−/− FVB nude	NKI animal facility	N/A
Software and algorithms
Living Image 4.5	Perkin Elmer	https://www.perkinelmer.com
Graphpad Prism 7.03	Graphpad	https://www.graphpad.com
Aperio ImageScope v12	Aperio Technologies	https://www.leicabiosystems.com
SPSS v22	SPSS Inc	https://www.ibm.com
Fiji / ImageJ 1.52n	NIH	https://imagej.nih.gov/ij/
Paravision software (v 6.0.1)	Bruker	https://www.bruker.com
ZEN Blue v3.1	Carl Zeiss	www.zeis.com
HALO v3.1.10076.423	Indica Labs	https://www.indicalab.com