Table 2.
Means and Corresponding SDs of the Ocular Parameters Measured in the Morning and in the Evening in the Three Groups of Eyes
| Morning | Evening | |||||||
|---|---|---|---|---|---|---|---|---|
| Normal Control | Hypertension | Glaucoma | FDR Adjusted | Normal Control | Hypertension | Glaucoma | FDR Adjusted | |
| Mean (SD) | Mean (SD) | Mean (SD) | P Value | Mean (SD) | Mean (SD) | Mean (SD) | P Value | |
| Macular CC perfusion area flow, mm2 | 2.110 (0.110) | 2.117 (0.111) | 2.125 (0.110) | 0.4745 | 2.137 (0.099) | 2.103 (0.103) | 2.120 (0.103) | 0.5471 |
| SCP-VD (%) | ||||||||
| Whole-SCP-VD | 51.337 (2.602) | 50.781 (2.783) | 45.726 (4.669) | <0.0001 | 51.504 (2.073) | 50.812 (2.907) | 46.069 (4.889) | <0.0001 |
| Fovea-SCP-VD | 21.674 (7.753) | 23.063 (6.792) | 18.210 (9.034) | 0.1902 | 21.609 (7.887) | 22.721 (6.228) | 18.774 (8.681) | 0.5855 |
| Para-fovea-SCP-VD | 54.052 (3.801) | 53.472 (2.786) | 49.687 (4.582) | 0.0005 | 54.037 (2.498) | 53.300 (3.609) | 50.154 (4.692) | 0.0022 |
| Macular thickness, µm | ||||||||
| Whole thickness | 282.074 (9.491) | 282.86 (12.813) | 266.923 (14.516) | 0.0006 | 281.685 (9.453) | 282.767 (13.25) | 266.282 (14.907) | 0.0002 |
| Fovea thickness | 257.611 (20.137) | 264.628 (30.236) | 247.897 (20.758) | 0.0165 | 258.333 (19.527) | 262.744 (23.044) | 248.128 (21.942) | 0.5769 |
| Para fovea thickness | 322.296 (11.424) | 324.512 (14.023) | 308.564 (18.519) | 0.0108 | 321.63 (11.42) | 324.14 (14.669) | 307.923 (18.987) | 0.0059 |
| GCC thickness, µm | ||||||||
| Whole GCC | 95.333 (4.911) | 94.000 (5.831) | 81.667 (12.244) | <0.0001 | 95.259 (4.938) | 93.791 (6.205) | 81.821 (12.314) | <0.0001 |
| Hemi inferior GCC | 94.796 (5.360) | 93.186 (6.013) | 81.59 (13.226) | <0.0001 | 94.704 (5.417) | 93.326 (6.232) | 81.564 (13.143) | <0.0001 |
| Hemi superior GCC | 96.056 (4.854) | 94.744 (6.184) | 82.128 (12.842) | <0.0001 | 95.704 (4.924) | 94.395 (6.329) | 81.641 (13.496) | <0.0001 |
The mean measurements of the CC perfusion area flow were not statistically different among the three groups either in the morning or in the evening. The mean measurements of all the other parameters investigated were statistically different among the three groups either in the morning or in the evening, except for the F-SCP-VD and the fovea-thick in the evening. The P values were obtained by linear mixed model, including as response variables the SCP-VD, the retinal and GCC thickness parameters, and as covariates the group, sex, systemic hypertension, age, axial length, and morning to evening changes in intraocular pressure. FDR-adjusted P values of the analysis of variance test for every parameter are shown.
CC, choriocapillaris; SCP-VD, superficial capillary plexus vessel density; GCC, ganglion cell complex; FDR, false discovery rate.
Statistically significant P values are in bold.