Table 2.
Showing comparison of demographic and baseline biochemical parameters between non-severe COVID-19 patients (cases) and healthy controls.
| Parameters | Non-severe COVID-19 patients (n = 72) | Matched healthy controls from CUBES (n = 72) | P |
|---|---|---|---|
| Age (years) | |||
| Mean ± SD Median (IQR) |
37.5 ± 13.7 36.0 (27.0–48.25) |
36.9 ± 13.7 35.0 (25.2–45.2) |
– |
| Male:Female ratio | 1.7:1.8 | 1.7:1.8 | – |
| Serum 25(OH)D (ng/ml) | |||
| Mean ± SD Median (IQR) |
9.8 ± 4.5 9.1 (6.8–12.3) |
9.6 ± 4.4 8.8 (6.7–11.4) |
– |
| Serum creatinine (mg/dl) | |||
| Mean ± SD Median (IQR) |
0.72 ± 0.20 0.70 (0.60–0.85) |
0.73 ± 0.17 0.71 (0.58–0.85) |
0.619* |
| Serum albumin (g/dl) | |||
| Mean ± SD Median (IQR) |
4.3 ± 0.6 4.4 (4.1–4.7) |
4.3 ± 0.3 4.2 (4.1–4.5) |
0.999# |
| Serum albumin-adjusted total calcium (mg/dl) | |||
| Mean ± SD Median (IQR) |
8.6 ± 0.4 8.6 (8.3–8.9) |
9.1 ± 0.5 9.2 (8.8–9.5) |
<0.001# |
| Serum non-adjusted total calcium (mg/dl) | |||
| Mean ± SD Median (IQR) |
8.8 ± 0.3 8.8 (8.5–9.2) |
9.3 ± 0.4 9.3 (9.0–9.7) |
<0.001# |
| Serum phosphate (mg/dl) | |||
| Mean ± SD Median (IQR) |
3.3 ± 0.7 3.3 (2.9–3.7) |
3.6 ± 0.5 3.6 (3.2–3.9) |
0.007# |
| Serum total ALP (IU/l) | |||
| Mean ± SD Median (IQR) |
103.2 ± 38.1 93.5 (78.2–123.7) |
100.2 ± 26.3 96.0 (83.2–112.0) |
0.771* |
| Serum magnesium (mg/dl)∧ | |||
| Mean ± SD Median (IQR) |
2.1 ± 0.2 2.1 (1.9–2.2) |
NA NA |
– |
| Serum CRP (mg/l) | |||
| Mean ± SD Median (IQR) |
21.6 ± 62.6 3.0 (1.1–8.8) |
NA NA |
– |
*
By Mann-Whitney U test.
#
By Independent Samples t-Test.
∧
Baseline data on serum magnesium was available in only 65 patients.
COVID-19, Novel coronavirus disease; CUBES, Chandigarh Urban Bone Epidemiological Study; SD, Standard deviation; IQR, Interquartile range; 25(OH)D, 25-hydroxyvitamin D; ALP, Alkaline phosphatase; CRP, C-reactive protein; NA, Not available.