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Effects of local oxygen enrichment on (A) body weight, (B) food intake, (C) water intake, (D) skin perfusion, and (E,F) locomotor activity of rats exposed to 4-week hypobaric hypoxia. All data are expressed as mean ± SD (n = 12). NC, normal control group; HAH, high-altitude hypoxia group; and HAHO, HAH with oxygen enrichment group. *p < 0.05 vs. the NC group, **p < 0.01 vs. the NC group, ***p < 0.001 vs. the NC group, and ###p < 0.001 vs. the HAH group.
