Table 4.
Biological processes of genes in the royalblue module in the weighted gene correlation network analysis.
| ID | Description | Count | P-value* | Genes |
|---|---|---|---|---|
| GO:0007155 | Cell adhesion | 10 | 2.98E−04 | VCAM1, CDH13, WISP1, CD33, FAP, POSTN, IL32, ADAM12, PCDH17, EMILIN1 |
| GO:0030198 | Extracellular matrix organization | 7 | 3.21E−04 | VCAM1, TTR, COL4A2, COL4A1, POSTN, COL5A2, EMILIN1 |
| GO:0032496 | Response to lipopolysaccharide | 5 | 0.007469291 | VCAM1, THBD, SLPI, TAC1, LIAS |
| GO:0071230 | Cellular response to amino acid stimulus | 3 | 0.02060527 | COL4A1, PDGFD, COL5A2 |
| GO:0071560 | Cellular response to transforming growth factor β stimulus | 3 | 0.022281384 | COL4A2, POSTN, PDGFD |
| GO:0007204 | Positive regulation of cytosolic calcium ion concentration | 4 | 0.025308179 | S1PR3, AGTR1, CYSLTR1, TAC1 |
| GO:0038063 | Collagen-activated tyrosine kinase receptor signaling pathway | 2 | 0.027901906 | COL4A2, COL4A1 |
| GO:0061737 | Leukotriene signaling pathway | 2 | 0.027901906 | RGS1, CYSLTR1 |
| GO:0030574 | Collagen catabolic process | 3 | 0.036513389 | COL4A2, COL4A1, COL5A2 |
| GO:0006952 | Defense response | 3 | 0.039687023 | CYSLTR1, GATA3, IL32 |
| GO:0070327 | Thyroid hormone transport | 2 | 0.041563188 | TTR, SLCO4A1 |
*
Significantly enriched Gene Ontology terms of differentially expressed genes were determined according to the cutoff values of P <0.05 and count ≥2.