Table 1.
Parts of the characteristics of the groups
| Con | AD | PD | DLB | PDD | P | |
|---|---|---|---|---|---|---|
| Gender | 11 Female/10 Male | 20 Female/14 Male | 3 Female/8 Male | 7 Female/9 Male | 2 Female/8 Male | 0.145 |
| Age at death(years old) | 87.2 ± 9.1 | 82.1 ± 8.0 | 76.4 ± 6.8 | 81.3 ± 6.2 | 77.4 ± 7.8 | 0.002 |
| PMI(h) | 15.4 ± 12.0 | 13.7 ± 6.3 | 14.9 ± 10.4 | 17.2 ± 9.7 | 11.2 ± 5.6 | 0.522 |
| Brain weight(g) | 1259 ± 174 | 1134 ± 147 | 1298 ± 120 | 1230 ± 152 | 1325 ± 176 | 0.001 |
| NIA‐Reagan criteria | 6 not met | 20 high likelihood | 3 not met | 1 high/ 1 low likelihood/9 not met | 1 low likelihood/6 not met | 0.000 |
| Braak NFT stage | 2 stage 0/ 7 stage I/ 8 stage II/3 stage III | 2 stage IV/14 stage V/19 stage VI | 5 stage I/ 2 stage II/ 4 stage III | 9 stage I/ 2 stage II/ 3 stage V /2 stage VI | 3 stageI/2 stageII/5 stageIII | 0.000 |
| Braak AB stage | All normal | All stageC | 3 normal/1 stage A/ 2 stageB/5 stageC | 1 normal/1 stage A/ 2 stageB/7 stageC | 1 normal/2 stageA/ 1 stageB/5 stageC | 0.000 |
| DLB(McKeith) criteria | ‐‐‐‐‐‐‐ | ‐‐‐‐‐‐ | 2 no Lewy bodies/1 diffuse type | 10 diffuse type | 7 diffuse type | 0.000 |
| Age onset(years old) | ‐‐‐‐‐‐ | 71.3 ± 10.3 | 63.8 ± 8.4 | 67.7 ± 9.7 | 62.9 ± 9.7 | 0.066 |
| Hallucination | ‐‐‐‐‐‐ | ‐‐‐‐‐‐ | 3 no/7 yes | 2 no/9 yes | 0 no/9 yes | 0.230 |
| Dyskinesia | ‐‐‐‐‐‐ | ‐‐‐‐‐‐ | 4 no/6 yes | 4 no/7 yes | 3 no/ 1 modest/5 yes | 0.986 |
| PD stage | ‐‐‐‐‐‐ | ‐‐‐‐‐‐ | 3 stage2/1 stage 2.5/4 stage3/2 stage4 | 2 stage2.5/3 stage 3/4 stage4/2 stage5 | 2 stage2/3 stage 3/3 stage4/1 stage5 | 0.143 |
| L‐Dopa responsiveness | ‐‐‐‐‐‐ | ‐‐‐‐‐‐ | 1 modest/9 yes | 1 no/1 modest/9 yes | 2 modest/7 yes | 0.721 |
Italic for p‐value indicates P < 0.05. If the total number of different levels of pathological criteria is less than the total number of cases, then some patients have not been diagnosed according to the pathological criteria.
PMI = postmortem interval, NIA‐Reagan criteria were divided into four levels: high, intermediate, low likelihood of dementia, and criteria not met. Braak NFT = Braak neurofibrillary tangle stage, ranging from stage I to VI with increasing histopathologic manifestations. Braak AB stage = Braak amyloid‐beta plaque stage, ranging from stage A to C with increasing histopathologic manifestations. DLB criteria were used to indicate the presence and distribution of Lewy body related pathology, including brainstem predominant type, intermediate or transitional type, diffuse type, or no Lewy bodies. Hallucination and dyskinesia denote there is accompanying hallucination or dyskinesia in PD patients. Dopamine responsiveness denotes whether the patients are responsive to L‐Dopa treatment. No report shown with “‐‐‐‐‐‐”.