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The pedigree maps of the three affected families. (a) Family with SMOC2 mutations. (b) Family with VPS4B mutations. (c) Family with SSUH2 mutations. The pedigree A is from the literature “Homozygosity Mapping and Candidate Prioritization Identify Mutations, Missed by Whole‐Exome Sequencing, in SMOC2, Causing Major Dental Developmental Defects” which is published in “The American Journal of Human Genetics” [Colour figure can be viewed at wileyonlinelibrary.com]
