TABLE 3.
Change of serum albumin levels over time (PP a )
| Follow‐up | n | Marginal mean b (g/dL) | Change from baseline (%) | Change from previous c (%) | Cumulative change (%) |
|---|---|---|---|---|---|
| Baseline | 468 | 4.03 (4.01‐4.05) | — | — | — |
| 15 days | 468 | 4.00 (3.98‐4.02) | −0.9 | −0.9 | −0.9 |
| 1 month | 468 | 3.98 (3.96‐4.00) | −1.3 | −0.4 | −1.3 |
| 3 months | 468 | 3.93 (3.91‐3.95) | −2.7 | −1.4 | −2.7 |
| 6 months | 468 | 3.95 (3.93‐3.97) | −2.0 | 0.7 | −2.0 |
| 9 months | 468 | 3.96 (3.94‐3.98) | −1.9 | 0.0 | −2.0 |
| 12 months | 468 | 3.99 (3.97‐4.01) | −1.2 | 0.8 | −1.2 |
Abbreviation: PP, per‐protocol defined as patients who received all treatments with the MCO membrane during the follow‐up period or until hospitalization that involved >12 dialysis sessions without MCO or death.
a
Only patients in the PP population who had baseline and all six scheduled serum albumin measurements during HDx were included in the analysis.
b
Marginal mean is the means estimation based on the fitted model in repeated measures and are presented as 95% confidence interval.
c
The percentual change from the last measurement value.