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. 2020 Jul 2;22(8):822–830. doi: 10.1111/bdi.12959

Table 3.

Consensus on pharmacological strategy for maintenance treatment

Bipolar I Bipolar II Rapid cycling
Li + AAP 1st 2nd 2nd
Li only Treatment of choice 1st 2nd
VAP + AAP No consensus 2nd 2nd
VAP only 2nd No consensus 2nd
LTG + AAP 2nd 2nd 2nd
LTG only 2nd 2nd No consensus
CBZ only 3rd 2nd 2nd
OLZ only 2nd 2nd 2nd
ARP only No consensus 2nd No consensus
QTP only 2nd 2nd 2nd
RIS only 3rd 3rd 2nd
ASP only 3rd 3rd 3rd
Li + VAP 2nd 2nd 2nd
Li + LTG 2nd 2nd 2nd
VAP + LTG No consensus No consensus No consensus
Li + AD 2nd No consensus 3rd
VAP + AD 3rd 3rd 3rd
LTG + AD 3rd 3rd 3rd
AD only 3rd. 3rd 3rd
MS + TH 3rd 3rd 3rd

Abbreviations: AD, antidepressant; AAP, atypical antipsychotic; ARP, aripiprazole; ASP, asenapine; CBZ, carbamazepine; CI, confidence interval; Li, lithium; LTG, lamotrigine; MS, mood stabilizer; OLZ, olanzapine; QTP, quetiapine; RIS, risperidone; SD, standard deviation; TH, thyroid hormone; VAP, valproic acid.