Table 2.
Median [IQR] SI levels (L/mU/min) comparison for the first 72 h between male and female cohorts using 6-h blocks
| Hours | Male cohort SI (× e−4) | female cohort SI (× e−4) | Median SIM−SIF [95% CI] (× e−4) | |
|---|---|---|---|---|
| Overall | ||||
| 0–71 | 3.1 [1.7 5.5] | 2.5 [1.5 4.0] | 0.6 [0.5 0.8]a | × |
| Day 1 | ||||
| 0–5 | 1.5 [0.5 2.7] | 1.3 [0.5 2.3] | 0.2 [0.0 0.5] | × |
| 6–11 | 2.2 [1.3 3.7] | 1.8 [0.7 3.3] | 0.4 [0.1 0.7] | × |
| 12–17 | 3.1 [1.7 4.8] | 2.2 [1.1 4.2] | 0.9 [0.5 1.3]a | × |
| 18–23 | 3.3 [1.8 5.9] | 2.4 [1.5 3.9] | 0.9 [0.5 1.2]a | × |
| Day 2 | ||||
| 24–29 | 3.3 [1.8 5.7] | 2.8 [1.6 4.0] | 0.5 [0.1 1.1] | × |
| 30–35 | 3.7 [2.1 6.5] | 2.7 [1.8 4.6] | 1.0 [0.5 1.4]a | × |
| 36–41 | 3.6 [2.0 6.0] | 2.8 [1.7 4.3] | 0.8 [0.2 1.4]a | × |
| 42–47 | 3.6 [2.0 6.0] | 2.9 [1.8 4.2] | 0.7 [0.2 1.1]a | × |
| Day 3 | ||||
| 48–53 | 4.0 [2.2 6.8] | 2.9 [1.9 4.4] | 1.1 [0.6 1.6]a | × |
| 54–59 | 4.4 [2.4 6.7] | 3.2 [1.9 4.8] | 1.1 [0.4 1.6]a | × |
| 60–65 | 3.8 [2.3 6.0] | 3.2 [2.1 4.6] | 0.6 [0.1 1.0] | × |
| 66–71 | 3.8 [2.5 5.7] | 3.0 [2.4 4.7] | 0.8 [0.4 1.2]a | × |
Equivalence is indicated by ⇔, Non-equivalence is indicated by × . Equivalence is a separate analysis to statistical difference. Hours where the medians are statistically different (95% CI does not cross zero) to P < 0.05 are in italic
aDifference remaining significant after Bonferroni correction (P < 0.004)