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. Author manuscript; available in PMC: 2021 Jan 21.
Published in final edited form as: Pharm Res. 2016 Aug 19;33(12):2904–2919. doi: 10.1007/s11095-016-2012-3

Fig. 3.

Fig. 3

Experimental brain metastases exhibit heterogeneous permeability and uptake of vinorelbine. Representative coronal brain section images at 0.5–8 h following i.v. administration of 3H-vinorelbine. (a1-c1) MDA-MB231BR brain metastasis localization and identification based on cresyl violet staining, yellow scale bar represents 2 mm. (a2-c2) Texas red fluorescence shows heterogeneous distribution and was used as marker of passive permeability in uninvolved brain and metastases. (a3-c3) Heterogeneous distribution of 3H-vinorelbine in brain metastases by QAR. Images across a row are of the same brain section.