Table 3.
The association of caregiver/patient predictors with caregiver emotional health and quality of life outcomes in models with number of GA domains impaired
| Independent variables | Anxiety (GAD-7) |
Distress | Depression (PHQ-2) |
SF-12 Physical Health |
SF-12 Mental Health |
SF-12 Total Score |
|---|---|---|---|---|---|---|
| OR (95% CI) | OR (95% CI) | OR (95% CI) | Coef. (95% CI) | Coef. (95% CI) | Coef. (95% CI) | |
| Caregiver Predictors | ||||||
| Age | 0.96 (0.94–0.99)* | 0.98 (0.96–1.00)^ | 0.97 (0.94–0.99)* | −0.13 (−0.21– −0.05)* | 0.23 (0.14–0.31)** | 0.08 (−0.04–0.19) |
| Female (vs male) | 0.93 (0.50–1.73) | 0.43 (0.25–0.74)* | 0.72 (0.37–1.42) | 2.14 (0.06–4.34) | 0.30 (−1.95–2.54) | 2.15 (−0.84–5.14) |
| Non-Hispanic white (vs other) | 1.17 (0.51–2.67) | 0.90 (0.45–1.84) | 0.80 (0.36–1.79) | 0.12 (−2.93–3.16) | −1.78 (−4.90–1.34) | −1.59 (−5.74–2.56) |
| Income > $50,000 + ‘Decline to answer’ (vs < $50,000) | 0.62 (0.37–1.03) | - | - | 2.40 (0.48–4.32)^ | - | 4.03 (1.39–6.66)* |
| Comorbidity | 2.94 (1.69–5.09)** | - | 3.13 (1.74–5.60)** | −8.11 (−10.09– −6.13)** | −3.99 (−6.00– −1.97)** | −11.86 (−14.57– −9.16)** |
| Patient Predictors | ||||||
| Cancer type (vs GI) | ||||||
| Lung | 1.22 (0.62–2.39) | 1.04 (0.58–1.88) | 0.84 (0.41–1.71) | −1.16 (−3.72–1.41) | 0.13 (−2.51–2.77) | −1.03 (−4.54–2.47) |
| Others | 0.84 (0.45–1.56) | 0.57 (0.34–0.97)^ | 0.68 (0.36–1.27) | −2.48 (−4.73– −0.24)^ | 0.64 (−1.66–2.94) | −1.85 (−4.91–1.21) |
| Distress (≥4) | 2.07 (1.22–3.52)* | 2.79 (1.76–4.44)** | - | - | −2.62 (−4.70 – −0.54)^ | −3.51 (−6.28 – −0.74)^ |
| Number of GA domains impaired | 0.98 (0.82–1.16) | 1.11 (0.96–1.29) | 1.29 (1.07–1.55)** | −1.24 (−1.85– −0.63)** | 0.00 (−0.66–0.65) | −1.14 (−2.01– −0.27)* |
Note: Lower scores for the GAD-7, distress thermometer, and PHQ-2 indicate lower anxiety, distress, and depression, respectively; while higher scores on the SF-12 indicate greater quality of life.
^
p-value<0.05,
*
p-value<0.01;
**
p-value<0.001
Predictors with empty cells were excluded in the stepwise procedure.
Abbreviations: GAD-7, generalized anxiety disorder 7-item scale; PHQ, patient health questionnaire; SF-12, 12-item short form health survey; OR, odds ratio; CI, confidence interval; Coef, coefficient; GI, gastrointestinal; GA, geriatric assessment