Figure 1.

The metabolic profile of female offspring at birth. A, Body weight of offspring at birth (female control, n = 32; male control, n = 27; female HFHS, n = 12; male HFHS, n = 19). B, Blood glucose and plasma TAG, leptin and insulin levels in the female offspring the day after birth (for glucose: control, n = 30; HFHS, n = 12; for TAG, leptin and insulin: control, n = 7–9; HFHS, n = 2–4). C, Lipid profiles in livers from two female pups/dam (TAG, FFA and PL content and composition, and ceramide content, see Figure S1 and Table S2 for additional data) (control, n = 12; HFHS, n = 6). D,E, Comparison of the hepatic lipid composition of offspring and the lipid profile of their mother's milk in a PLS analysis. Gender and diet effects on body weight were estimated by 2‐way ANOVA, and groups compared by t‐test. ^* P < .05