Table 1.

Rigid protein–ligand docking performance of autodock vina, gwovina, ledock, plant, and smina on the Astex dataset (85 complexes)

	Best‐scoring pose RMSD (Å)	Average RMSD (Å)	Best‐scoring pose success rate	Average success rate	Pearson's correlation coefficient, R	Runtime (s)
autodock vina	1.84	1.93	72.94	71.65	0.51	10.67
smina	1.84	1.93	74.12	72.24	0.51	12.81
ledock	2.74	2.77	61.18	55.65	0.28	7.53
plant	2.10	4.25	77.65	51.76	0.29	14.21
GWOVina (this study)	1.74	1.87	75.29	72.94	0.51	5.76

The best results are printed in bold.