Table 2. Antimycobacterial Activity of 8–37 Compounds.
compd | C log Pa | MIC (μM) | compd | C log Pa | MIC (μM) |
---|---|---|---|---|---|
8 | 3.34 | 61.48 | 23 | 2.22 | 65.68 |
9 | 3.35 | 57.98 | 24 | 1.76 | 14.98 |
10 | 2.22 | 7.90 | 25 | 3.29 | 27.96 |
11 | 2.36 | 30.25 | 26 | 3.45 | 68.96 |
12 | 2.93 | 29.13 | 27 | 3.64 | 28.2 |
13 | 2.20 | 15.20 | 28 | 3.8 | 7.00 |
14 | 1.35 | 8.42 | 29 | 3.64 | 14.01 |
15 | 1.40 | 57.76 | 30 | 3.23 | 12.75 |
16 | 2.06 | 6.96 | 31 | 3.45 | 15.78 |
17 | 2.09 | 13.92 | 32 | 3.57 | 14.67 |
18 | 1.87 | 13.98 | 33 | 4.87 | 53.87 |
19 | 3.30 | 6.98 | 34 | 4.87 | 62.49 |
20 | 2.17 | 14.99 | 35 | 3.92 | 29.3 |
21 | 2.15 | 15.06 | 36 | 4.15 | 28.27 |
22 | 2.41 | 7.86 | 37 | 2.46 | 34.71 |
Isoniazid | 0.78 | ||||
Ethambutol | 7.89 | ||||
Rifampicin | 0.21 |
C log P calculated using Chemdraw Ultra 12.0 software by Cambridge Soft.