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. 2021 Jan 7;6(2):1657–1667. doi: 10.1021/acsomega.0c05690

Table 2. Antimycobacterial Activity of 837 Compounds.

compd C log Pa MIC (μM) compd C log Pa MIC (μM)
8 3.34 61.48 23 2.22 65.68
9 3.35 57.98 24 1.76 14.98
10 2.22 7.90 25 3.29 27.96
11 2.36 30.25 26 3.45 68.96
12 2.93 29.13 27 3.64 28.2
13 2.20 15.20 28 3.8 7.00
14 1.35 8.42 29 3.64 14.01
15 1.40 57.76 30 3.23 12.75
16 2.06 6.96 31 3.45 15.78
17 2.09 13.92 32 3.57 14.67
18 1.87 13.98 33 4.87 53.87
19 3.30 6.98 34 4.87 62.49
20 2.17 14.99 35 3.92 29.3
21 2.15 15.06 36 4.15 28.27
22 2.41 7.86 37 2.46 34.71
Isoniazid         0.78
Ethambutol         7.89
Rifampicin         0.21
a

C log P calculated using Chemdraw Ultra 12.0 software by Cambridge Soft.