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Effects of domain swapping on catalytic rates in the DH domain. (A) pH optima of cellobiose conversion in CDHs with a DHA when using the two-electron acceptor 2,6-dichloroindophenol. (B) pH optima of CDHs with a DHB using the same substrate and cosubstrate as in (A). (C) FAD reduction rate in all CDHs measured at 449 nm (kobs449) for increasing cellobiose concentrations.
