Table 1.
Baseline characteristics of patients and biochemical analyses before and after MIP
| Total population | |
|---|---|
| n = 117 | |
| Male, n (%) | 35 (29.9) |
| Age (year) | 60 ± 13 |
| BMI (kg/m2) | 25.5 ± 4.0 |
| Symptomatic hypercalcemia | 19 (16.2) |
| Nephrolithiasis | 36 (30.8) |
| Peptic ulcers | 3 (2.6) |
| Pancreatitis | 4 (3.4) |
| Cardiovascular disease | 18 (15.4) |
| Hypertension | 55 (47.0) |
| Osteoporosis | 27 (23.1) |
| Fragility fracture | 3 (2.6) |
| Neuropsychiatric/neurocognitive symptoms | 7 (6.0) |
| Neuromuscular symptoms | 6 (5.1) |
| CrCl < 60 ml/min | 11 (9.4) |
| Others symptoms | 16 (13.7) |
| Serum creatinine (mg/dL) | 1.2 ± 0.7 |
| eGFR (mL/min) | 89.2 ± 38.1 |
| Preoperative serum calcium (mg/dL) | 11.8 ± 2.1 |
| 25-OH vitamin D (ng/mL) | 53.5 ± 15.6 |
| 24-h urinary calcium | 279.1 ± 112.1 |
| Preoperatve iPTH (pg/ml) | 459.2 ± 602.1 |
| Intraoperative iPTH (pg/ml) | 59.7 ± 71.1 |
| Postoperative iPTH (pg/ml) | 25.3 ± 17.3 |
| 6 months iPTH (pg/ml) | 23.0 ± 9.8 |
| I postoperative day serum calcium (mg/dL) | 9.1 ± 0.6 |
| II postoperative day serum calcium (mg/dL) | 9.0 ± 0.6 |
| III postoperative day serum calcium (mg/dL) | 8.9 ± 0.5 |
| Follow-up time (months) | 60 ± 1 |
| Temporary hypoparathyroidism | 7 (6.0) |
| Permanent hypoparathyroidism | 0 (0.0) |
| Persistent hyperparathyroidism | 0 (0.0) |
| Recurrence hyperparathyroidism | 0 (0.0) |
| Disease relapse | 0 (0.0) |
Data are shown as mean ± standard deviation or number (%)
Abbreviations: MIP minimally invasive parathyroidectomy, BMI body mass index, CrCl creatinine clearance, eGFR estimated glomerular filtration rate, 25-OH vitamin D 25-hydroxyvitamin D3, iPTH intact-parathyroid hormone, PTX 6 months iPTH intact-parathyroid hormone measurement 6 months later the surgery intervention