Table 4.
Anatomical pathology findings comparison between TA (group A) and APA (group B)
| Group A typical adenoma |
Group B atypical adenoma |
P value | |
|---|---|---|---|
| n = 107 | n = 10 | ||
| Single gland disease | 100 (93.5) | 10 (100.0) | 1.000 |
| Double typical adenoma | 7 (6.5) | 0(0.0) | 1.000 |
| Size of parathyroid gland (mm) a | 23 ± 13 | 25 ± 30 | 0.001 |
| Weight of parathyroid gland (mg) | 40 ± 16 | 120 ± 64 | < 0.001 |
| Clinical/intraoperative adherence | 0 (0.0) | 0 (0.0) | – |
| Pseudocapsular invasion | 0 (0.0) | 4 (40.0) | < 0.001 |
| Bands of fibrosis | 4 (3.7) | 5 (50.0) | < 0.001 |
| Pronounced trabecular growth | 7 (6.5) | 6 (60.0) | < 0.001 |
| Mitotic rates of > 1/10 HPFS | 2 (1.9) | 6 (60.0) | < 0.001 |
| Tumor necrosisb | 0 (0.0) | 1 (10.0) | 0.085 |
| Nuclear pleomorphism | 2 (1.9) | 2 (20.0) | 0.036 |
| Cystic degeneration | 8 (7.5) | 2 (20.0) | 0.204 |
| Thick capsule | 0 (0.0) | 4 (40.0) | < 0.001 |
| Hemosiderin deposition | 3 (2.8) | 2 (20.0) | 0.058 |
| Hematic extravasion | 5 (4.7) | 2 (20.0) | 0.110 |
| Ki-67+ < 1% | 11 (10.3) | 0 (0.0) | 0.598 |
| Ki-67+ > 4% | 0 (0.0) | 4 (40.0) | < 0.001 |
| Galactin-3 + | 22 (20.6) | 7 (70.0) | 0.002 |
| PGP 9.5 + | 13 (12.1) | 4 (40.0) | 0.038 |
Data are show as mean ± standard deviation or number (%)
Abbreviations: HPFS high-power fields
aMaximum diameter
bNot associated with tumorous infarction or fine-needle aspiration