Table 1.
Fate-mapping studies of NG2 glia in different transgenic mice
| Short name | Type (TgH/TgN/ BAC/PAC) | Reporter | Region | Recombined NG2 glia (%) | Recombined cell types | Reference(s) | ||
|---|---|---|---|---|---|---|---|---|
| OL Lineage | Astrocyte | Neuron | ||||||
| NG2-CreZhu | BAC | Z/EG | brain | ~86 | + | + | – | Zhu et al. (2008a, b) |
| Z/EG | spinal cord | ~70 | + | + | Not mentioned | |||
| NG2-CreERTZhu | BAC | Z/EG | brain | < 2 | + | + (from Embryonic) | + | Zhu et al. (2011) |
| Rosa26-EYFP | brain | ~45 | + | Not mentioned | – | |||
| Rosa26-tdTomato | brain | ~80 | + | - | + | Robins et al. (2013) | ||
| NG2-CreTsoa | BAC | Rosa26-LacZ | brain | ~99 | + | Not mentioned | + | Tsoa et al. (2014) |
| NG2-CreERT2Huang | TgH | Rosa26- tdTomato | brain | ~95 | + | + (from Embryonic) | + | Huang et al. (2014, 2018, 2019) |
| Rosa26-EYFP | brain | ~75 | + | Not mentioned | + | |||
| Rosa26-tdTomato | spinal cord | Not mentioned | + | – | + | |||
| PDGFRα-CreERT2Rivers | PAC | brain | ~47 | + | – | + (in PC) | Rivers et al. (2008) | |
| Rosa26-EYFP | spinal cord | ~40 | + | – | – | Zawadzka et al. (2010) | ||
| PDGFRα-CreERTKang | BAC | Rosa26-mGFP | brain | ~86 | + | – | + | Kang et al. (2010) |
| Rosa26-EYFP | brain | ~87 | + | – | + | |||
| Z/EG | brain | ~42 | + | – | + | |||
| PLP-CreERTDoerflinger | TgN | Rosa26-EYFP | brain | ~17 | + | + | + (in PC) | Guo et al. (2009, 2010) |
| spinal cord | ~27 | + | + | + | ||||
| Rosa26-EYFP | cerebellum | Not mentioned | + | + | – | Chung et al. (2013) | ||
| Olig2-CreERTTakebayashi | TgH | Rosa26-EYFP | cerebellum | Not mentioned | + | + | – | |
| Rosa26-EYFP | brain | Not mentioned | + | + | – | Dimou et al. (2008) | ||
| Z/EG | brain | Not mentioned | + | + | – | |||
+: Defined cell types were detected; –: defined cell types were not detected; BAC: bacterial artificial chromosome; NG2: nerve-glia antigen 2; TgH: transgene homologous recombination; TgN: transgene non-homologous recombination; PAC: phage artificial chromosome; PC: piriform cortex.