FIGURE 2.

Resveratrol increases IMCL in type I muscle fibres. Effect of in vivo resveratrol supplementation of 150 mg/day trans‐resveratrol on IMCL (a), LD number (b) and LD size (c) in human muscle biopsies. IMCL was determined by lipid area (Bodipy staining)/cell area * 100%. Parameters were analysed in type I muscle fibres, type II muscle fibres and for both fibre types combined. Data are presented as mean ± SEM (n = 10); *p < 0.05 (paired t‐test). Images are representative for IMCL in type I muscle fibres (d) and type II (e) muscle fibres with placebo on the left and resveratrol on the right. Cell membranes are stained in blue and LDs in green. Scale bar is 20 µm (d) or 10 µm (e)